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<p class=3DMsoNormal align=3Dcenter style=3D'text-align:center'><span
style=3D'font-size:14.0pt'>Swine (H1N1) Flu Update No. 3<o:p></o:p></span><=
/p>

<p class=3DMsoNormal align=3Dcenter style=3D'text-align:center'><span
style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-many authorities are=
 now
altering their concerns to cautious optimism about the original estimates of
the seriousness of the H1N1 situation<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-as of 6:30 this even=
ing H1N1
has affected 286 people in 36 states in the US (as opposed to about 12 peop=
le
last week); about 1100 people have been affected worldwide in 21 countries<=
o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-symptoms and the mor=
tality
rate now seem to be no worse that those of the usual seasonal flu<o:p></o:p=
></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-death <u>rate</u> in=
 <st1:country-region
w:st=3D"on"><st1:place w:st=3D"on">Mexico</st1:place></st1:country-region> =
now also
seems to be not as high as originally thought<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-H1N1 appears to be a=
 whole
new kind of flu virus than those that cause the usual seasonal flu; it occu=
rs
occasionally in pigs and those in contact with pigs; what seems so unusual =
this
time is the rate of transmission from person-to-person<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-those affected, inst=
ead of
coming from the groups of very young and very old now seem to be from the
young, healthy adult population;<span style=3D'mso-spacerun:yes'>&nbsp;
</span>this may be the result of a &#8220;cytokine storm,&#8221; or an
over-exuberant response of the person&#8217;s own immune system<o:p></o:p><=
/span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-the term <u>pandemic=
</u>
refers to how <u>widespread</u> the infection if, not how <u>severe</u> its
symptoms are; i.e., it could be a very mild pandemic<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-there are usually ab=
out
36,000 deaths/year in the <st1:country-region w:st=3D"on"><st1:place w:st=
=3D"on">US</st1:place></st1:country-region>
from the usual seasonal flu; the number of deaths associate with H1N1 infec=
tion
seem to be similar<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>-in 1977-18, the virus
bounced back later in the season and struck severely; viruses, however,
don&#8217;t read history books and could bounce back worse, milder, or not =
at
all<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><o:p>&nbsp;</o:p></sp=
an></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'><span
style=3D'mso-spacerun:yes'>&nbsp;</span><o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:14.0pt'>Henry Sanders, MD<o:p=
></o:p></span></p>

<p class=3DMsoNormal><st1:place w:st=3D"on"><st1:PlaceName w:st=3D"on"><span
  style=3D'font-size:14.0pt'>Exeter</span></st1:PlaceName><span style=3D'fo=
nt-size:
 14.0pt'> <st1:PlaceType w:st=3D"on">Town</st1:PlaceType></span></st1:place=
><span
style=3D'font-size:14.0pt'> Physician<o:p></o:p></span></p>

<p class=3DMsoNormal><st1:date Year=3D"2009" Day=3D"4" Month=3D"5" w:st=3D"=
on"><span
 style=3D'font-size:14.0pt'>5/4/09</span></st1:date><span style=3D'font-siz=
e:14.0pt'><o:p></o:p></span></p>

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